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| Caption | Schematic of the Tg(APOE-rtTA*M2,tetO-Rgs16)#Tmw transgene. A, The transgenes ApoE::TA and TetON::Rgs16 were co-injected to obtain transgenic RGS16 tagged at the C terminus with a triple repeat of the Myc epitope (white box following mRgs16). The human ApoE promoter drives the Tet activator protein (TAS2s-M2) expression in liver. TAS2s-M2 binds TREs to induce expression of transgenic Rgs16-myc3 (TgR16) only in the presence of doxycycline. | ||||
| Copyright | This image is from Pashkov V, J Biol Chem 2011 Apr 29;286(17):15116-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:172091 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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