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Caption Schematic of the insertion sites of the Asf1aGt(AL0673)Wtsi, Del(10Mcm9-Asf1a)1Byg, Mcm9Gt(AW0655)Wtsi, and Mcm9Gt(XG743)Byg gene traps. (A) Mcm9 has 2 isoforms: Mcm9s and Mcm9L. The former uses an alternative splice site in exon 7 that results in termination. Triangles depict the insertion sites of the gene traps. XE518 created a deletion that includes Asf1a. Locations of polymorphic SNPs used for measuring deletion size in the Del(10Mcm9-Asf1a)1Byg (Mcm9XE518) allele are indicated. These are: (Left to Right) rs51772485, rs46087546, rs51382030, rs51176035, rs47659858, and rs49316622. The Asf1a gene trap is located 640-bp downstream of exon 2.
Copyright This image is from Hartford SA, Proc Natl Acad Sci U S A 2011 Oct 25;108(43):17702-7. Copyright 2011 National Academy of Sciences, U.S.A. J:177420
Associated
Alleles
Symbol Name
Asf1aGt(AL0673)Wtsi anti-silencing function 1A histone chaperone; gene trap AL0673, Wellcome Trust Sanger Institute
Del(10Mcm9-Asf1a)1Byg gene trap XE518 induced deletion 1, BayGenomics
Mcm9Gt(AW0655)Wtsi minichromosome maintenance 9 homologous recombination repair factor; gene trap AW0655, Wellcome Trust Sanger Institute
Mcm9Gt(XG743)Byg minichromosome maintenance 9 homologous recombination repair factor; gene trap XG743, BayGenomics
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12/10/2024
MGI 6.24 		The Jackson Laboratory