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Molecular Image Detail
Image
Caption Generation of the Sprntm1Geno allele. (A) Diagrammatic representation of genomic structure of Sprn locus and targeting vector. The targeting vector was constructed by replacing ~5.6 kb of genomic DNA downstream of the start codon, including exon 1 and the majority of exon 2, with a neomycin resistance gene flanked by loxP sequences. 06SH1 and 06Sh3a are the polyclonal antibodies, which have been raised against Sho. N3 corresponds to the full-length protein (mSho), N1 and C1 are processed fragments, N and C terminal, respectively.
Copyright This image is from Daude N, Proc Natl Acad Sci U S A 2012 Jun 5;109(23):9035-40. Copyright 2012 National Academy of Sciences, U.S.A. J:184837
Associated
Alleles
Symbol Name
Sprntm1Geno shadow of prion protein; targeted mutation 1, Genoway

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory