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Molecular Image Detail
Image
Caption Generation of an allelic series of mutations (Slc20a1tm1Lbek, Slc20a1tm1.1Lbek and Slc20a1tm1.2Lbek) at the Slc20a1 (PiT1) locus. (A) Schematic representation of the alleles and targeting vector representing intronic DNA (horizontal lines), exons (black boxes) a neo cassette flanked by frt sites (unfilled box) and a diphtheria toxin cassette (hatched box). Flp-mediated recombination at frt sites generates the Slc20a1tm1.1Lbek (PiT1flox) allele, whereas Cre-mediated recombination at loxP sites (open triangles) generates the Slc20a1tm1.2Lbek (PiT1delta5) allele. The positions of restriction sites used for Southern blot screening are shown: E, EcoRV; N, NheI; A, ApaLI.
Copyright This image is from Beck L, PLoS One 2010;5(2):e9148, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:157997
Associated
Alleles
Symbol Name
Slc20a1tm1.1Lbek solute carrier family 20, member 1; targeted mutation 1.1, Laurent Beck
Slc20a1tm1.2Lbek solute carrier family 20, member 1; targeted mutation 1.2, Laurent Beck
Slc20a1tm1Lbek solute carrier family 20, member 1; targeted mutation 1, Laurent Beck

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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory