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Caption Generation of the Lpar5tm1Jch allele. A, schematic diagram of the Lpar5 gene targeting strategy. To generate the targeting vector, a portion of the Lpar5 coding region was removed and replaced in frame by enhanced GFP (middle panel). ES cell clones positive for homologous recombination were identified by digestion of genomic DNA with HindIII and Southern blotting with the external probe shown in the top panel. ES cell clones with non-homologous recombination events showed a 7-kb band, whereas clones with homologously recombined DNA produced a 4.9-kb band.
Copyright This image is from Lin ME, J Biol Chem 2012 May 18;287(21):17608-17 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:185624
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Alleles
Symbol Name
Lpar5tm1Jch lysophosphatidic acid receptor 5; targeted mutation 1, Jerold Chun

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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory