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| Caption | Generation of floxed Sptlc2tm2.1Jia (Sptlc2-Flox) allele. A, strategy. A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 5' loxP site was inserted downstream of exon 1. Flp mediated recombination removed the neo cassette leaving exon 1 floxed. Cre-mediated recombination can be used to generate tissue-specific deletion. A 250-bp fragment was used as a probe for Southern blot analysis. | ||||
| Copyright | This image is from Li Z, J Biol Chem 2009 Sep 25;284(39):27010-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:155507 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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