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Caption Generation of the Tdp2tm1Huy and Tdp2tm1.1Huy alleles. Scheme showing the strategy for targeted deletion of the first three exons of Tdp2 in mouse. The wild-type (Tdp2+), conditional(Tdp2flEx13,neo) and deleted (Tdp2fldelta) alleles are depicted. The EcoRI-EcoRI fragment of Tdp2 was used in the targeting construct. Southern-blot analysis of PstI-digested DNA from wild-type (+/+), heterozygous (+/fldelta) and knock-out (fldelta/fldelta) mice, using the indicatedprobe (red line), is shown (bottom right).
Copyright This image is from Gomez-Herreros F, PLoS Genet 2013 Mar;9(3):e1003226, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195301
Associated
Alleles
Symbol Name
Tdp2tm1.1Huy tyrosyl-DNA phosphodiesterase 2; targeted mutation 1.1, Danny Huylebroeck
Tdp2tm1Huy tyrosyl-DNA phosphodiesterase 2; targeted mutation 1, Danny Huylebroeck

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory