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| Caption | Generation of the Pgap6tm1Osb allele. (A) Construction of Tmem8 (Pgap6) targeting vector. (top) Wild-type locus. (middle) Tmem8 targeting construct containing two FRT sites, three loxP sites, a splicing acceptor (SA) site, an internal ribosome entry site (IRES), LacZ gene, and neomycin resistance gene (neo) driven by human Beta-actin promoter (hBactP) for positive selection. Gray and white boxes indicate coding and noncoding exons, respectively. (bottom) KO construct targeted Tmem8 genomic locus. p1, p2 and p3 indicate primer postions used in B. | ||||
| Copyright | This image is from Lee GH, J Cell Biol 2016 Dec 5;215(5):705-718, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:258200 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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