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| Caption | Schematic diagram of construct used to produce transgenic Tg(SOD1*G85R/EYFP)641Alho (G85R SOD-YFP) mice. The 5' and 3' regions and introns are indicated by the striped bars for the mutant G85R. The coding sequence for EYFP (Clontech) was fused in frame at the last codon of SOD1 in exon V with a short linker. The G85R mutation was introduced into exon IV by oligonucleotide-directed mutagenesis of a restriction fragment, which was then substituted for the wild-type fragment. The sizes of the introns and exons are not to scale. | ||||
| Copyright | This image is from Wang J, Proc Natl Acad Sci U S A 2009 Feb 3;106(5):1392-7. Copyright 2009 National Academy of Sciences, U.S.A. J:144475 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/09/2024 MGI 6.24 |
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