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| Caption | Comparison of Hephl1 in wild-type (WT) and Hephl1cw/Hephl1cw (cw/cw) mutant mice. (A) All coding regions were sequenced in WT and in mutant genomic DNA, but only a single difference, at the Intron 10-11 to Exon 11 boundary was found. Shown here are nucleotides 9:15076971 to 9:15076921 from reference sequence GRCm38.p6 (EMGS 2019); with intronic sequences in lower case, exonic sequences in upper case. The pyrimidine-rich tract and the 5'-AG-3' dinucleotide that compose the standard splice-acceptor signal are indicated over the sequence labeled WT. The A-to-G substitution found in the mutants (at position 9:15076948) is indicated by a red asterisk on the sequence labeled cw. | ||||
| Copyright | This image is from Eragene S, Mol Genet Metab Rep 2019;20():, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-NoDerivatives 4.0 License. J:276072 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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