| Image |
|
||||
| Caption | Comparison of Hephl1 in wild-type (WT) and Hephl1cw-2J/Hephl1cw-2J mutant mice. All coding regions were sequenced in WT and in Hephl1cw-2J/Hephl1cw-2J mutant genomic DNA, but only a single difference, in Exon 14, was found. This mutation, the insertion of a single A residue in the mutants compared to WT, is indicated with a red asterisk on the sequence labeled cw2J. The sequence shown here includes nucleotides 9:15067163 to 9:15067125, from reference sequence GRCm38.p6 (EMGS 2019). This insertion is predicted to shift the translational reading frame on mutant transcripts, generating seven novel amino acids (residues 820-826, shown in red) followed by an early, out-of-frame stop codon. | ||||
| Copyright | This image is from Eragene S, Mol Genet Metab Rep 2019;20():, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-NoDerivatives 4.0 License. J:276072 | ||||
|
Associated Alleles |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/19/2024 MGI 6.24 |
|
|
|
||
Analysis Tools