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Molecular Image Detail
Image
Caption Identification of the mutation in the Megf8hlb611 allele. (A). A 15 BAC contig was obtained spanning the 2.2-Mb critical region containing the mutation in chromosome 7 (25,837,390-28,028,384 b, NCBI m37 assembly). Sequencing showed a T to C substitution, causing cysteine (C) to arginine (R) amino acid replacement in Megf8, and another C to A substitution in a noncoding intergenic region.
Copyright This image is from Zhang Z, Proc Natl Acad Sci U S A 2009 Mar 3;106(9):3219-24. Copyright 2009 National Academy of Sciences, U.S.A. J:146805
Associated
Alleles
Symbol Name
Megf8hlb611 multiple EGF-like-domains 8; heart, lung and blood 611

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory