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Caption Generation of the Thrbtm6.1Few allele. Schematic strategy of R429Q mutation introduction into the mouse Thrb (TR-Beta) gene by homologous recombination. Diagrams show the wild-type (WT) Thrb locus, the targeting vectors, ES-target alleles, and the F1 mutant allele after the neo cassette (ACN cassette) is self-excised.
Copyright This image is from Machado DS, Proc Natl Acad Sci U S A 2009 Jun 9;106(23):9441-6. Copyright 2009 National Academy of Sciences, U.S.A. J:150008
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Alleles
Symbol Name
Thrbtm6.1Few thyroid hormone receptor beta; targeted mutation 6.1, Fredric E Wondisford

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory