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Caption Generation of the Phlpp1tm1Saco and Phlpp1tm1.1Saco alleles. Targeting strategy to disrupt the PHLPP1 gene. Shown are the wild-type (WT) allele, the targeting vector, the targeted floxed allele Phlpp1tm1Saco, and the deleted Phlpp1tm1.1Saco allele generated by cre-mediated recombination of the floxed allele. The DNA probe used for screening the Southern blots is marked by a dotted box, and the PCR primers used for genotyping are indicated by small arrows.
Copyright This image is from Masubuchi S, Proc Natl Acad Sci U S A 2010 Jan 26;107(4):1642-7. Copyright 2010 National Academy of Sciences, U.S.A. J:156530
Associated
Alleles
Symbol Name
Phlpp1tm1.1Saco PH domain and leucine rich repeat protein phosphatase 1; targeted mutation 1.1, Paolo Sassone-Corsi
Phlpp1tm1Saco PH domain and leucine rich repeat protein phosphatase 1; targeted mutation 1, Paolo Sassone-Corsi
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11/19/2024
MGI 6.24 		The Jackson Laboratory