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| Caption | Generation of the ErbinGt(BGA258)Byg allele. The Beta-gal gene (Beta-geo) was inserted downstream of exon 20 of the erbin gene, producing a chimerical mRNA of erbin and Beta-geo mRNAs. The mRNA encodes a fusion protein containing the N-terminal 693 aa residues and Beta-gal (thus named as Erbin1-693Betagal). (A) Schematic diagrams of the genetrap vector pGT2Lxf insertion between exons 20 and 21. pGT2Lxf contains En2, the splice acceptor/ Engrailed-2 exon and Beta-geo. Arrows indicate the orientation of genotyping primers 6, 6' and 6". | ||||
| Copyright | This image is from Tao Y, Proc Natl Acad Sci U S A 2009 Jun 9;106(23):9477-82. Copyright 2009 National Academy of Sciences, U.S.A. J:149996 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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