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Molecular Image Detail
Image
Caption Generation of the Mcpt8tm1.1(HBEGF)Hkar allele. (A) Schematic diagram of Mcpt8DTR targeting construct. Exons are shown as black boxes. The restriction sites indicated are as follows: E, EcoRV; S, SalI; A, AflII. A SalI site engineered in the 3' untranslated region of the Mcpt8 gene was used to clone the IRES-DTR-EGFP-loxP-Neo-loxP cassettes. Neo cassette was removed by Cre-mediated recombination after mating with CAG-cre deleter mice.
Copyright This image is from Wada T, J Clin Invest 2010 Aug 2;120(8):2867-75 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:163761
Associated
Alleles
Symbol Name
Mcpt8tm1.1(HBEGF)Hkar mast cell protease 8; targeted mutation 1.1, Hajime Karasuyama

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory