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| Caption | Generation of the Mir33tm1.1Koho allele. (A) Strategy to generate miR-33-deficient mice by homologous recombination. The premiR-33 sequence was replaced with a neomycin resistance cassette (pgk-gb2-Neo) flanked by loxP sites. The neomycin resistance cassette was removed in the mouse germ line by breeding heterozygous mice with Ayu-1 Cre mice, which express Cre recombinase in multiple tissues, including the germ line. | ||||
| Copyright | This image is from Horie T, Proc Natl Acad Sci U S A 2010 Oct 5;107(40):17321-6. Copyright 2010 National Academy of Sciences, U.S.A. J:165420 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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