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| Caption | Generation of the Sox9tm1(cre/ERT2)Haak allele. Targeting strategy for the insertion of the tamoxifen-inducible CreERT2 construct into the 3' UTR of the Sox9 gene. (a) Structure of the genomic Sox9 gene, targeting vector, and targeted allele. Exons are depicted as filled boxes, and intronic sequences are shown as solid lines. IRES-CreERT2-pA and the FRT-PGK-neo-bpA cassettes are depicted as open boxes. The FRT-PGK-neo-bpA cassette was not removed in the final targeted allele. DNA fragments identified in the Southern blot analysis are indicated by double arrows, with the restriction enzymes and the probe. iresCreERT2, IRES-CreERT2-pA; PGKneo, PGK-neo-bpA; B, BamHI; P, PstI; X, XbaI; H, HpaI. | ||||
| Copyright | This image is from Soeda T, Genesis 2010 Nov;48(11):635-44, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:166624 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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