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| Caption | Generation of the Hormad1tm1Rajk allele. (A) Disruption of the Hormad1 locus. The targeting construct and schematized genomic locus of Hormad1 are shown. The neo cassette replaced HORMA domain encoding highly conserved exons 4 and 5, and introduced an Xba I restriction enzyme site into the locus. This Xba I site was used as a diagnostic for Southern blot analysis of ES cells electroporated with the targeting vector (data not shown). Arrows indicate genotyping primers used to distinguish wild-type and mutant alleles in the transgenic animals. | ||||
| Copyright | This image is from Shin YH, PLoS Genet 2010;6(11):e1001190, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:167522 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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