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| Caption | Generation of the Kcnj16tm1Pess allele. A, targeting strategy. Top, restriction map of the wild-type (WT) Kir5.1 (Kcnj16) gene used to construct the targeting vector. The entire 419-amino acid sequence of Kir5.1 is encoded on a single exon. Dotted lines define the limits of the recombinagenic arms. Middle, targeting construct in which a neomycin resistance gene (Neo) was inserted to replace amino acids 1 to 360 of the Kir5.1 open reading frame. Bottom, targeted Kcnj16 allele. Restriction enzyme sites: B, BamHI; X, XbaI; R, EcoRI. | ||||
| Copyright | This image is from D'Adamo MC, J Biol Chem 2011 Jan 7;286(1):192-8 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:167533 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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