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| Caption | Generation of the Dbitm1Smdp allele. Targeting of the Dbi (Acbp) gene (a) was performed using a sequence replacement vector (b), which contained a cassette for negative selection with gancyclovir (thymidine kinase gene (Tk) under control of the Pgk1 promoter) upstream of the region of homology and a cassette for positive selection with neomycin (loxP-flanked neomycin resistance cassette under the control of the PGK-1 promoter) replacing the Dbi exon 2 and parts of introns 1 and 2. Homologous recombination results in the targeted Dbitm1Smdp allele (c). | ||||
| Copyright | This image is from Neess D, J Biol Chem 2011 Feb 4;286(5):3460-72 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:168744 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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