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| Caption | Generation of the Hmgn1tm1Mbus allele. Diagram detailing structural domains of HMGN1 protein and the mutations in them used in this study are shown. Each rectangle represents an exon from the coding sequence of the gene in question; the amino acids at the boundaries of the exons are marked above the diagram. The exons deleted in creating the functional knock-out for HMGN1 variant is denoted by the black curved line below the diagram, and the amino acid positions at the boundary of the excised domains, which are missing in the mutant mouse, are marked on either side of the curved line. NLS, nuclear localization sequence; NBD, nucleosome binding domain. RD, regulatory domain. | ||||
| Copyright | This image is from Kugler JE, J Biol Chem 2013 Jun 7;288(23):16690-703 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199604 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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