Molecular Image Detail

Image

Caption

Generation of the Hmgn5^tm1.2Mbus allele. Diagram detailing structural domains of HMGN5 protein and the mutations in them used in this study are shown. Each rectangle represents an exon from the coding sequence of the gene in question; the amino acids at the boundaries of the exons are marked above the diagram. The exons deleted in creating the functional knock-out for the HMGN5 variant are denoted by the black curved line below the diagram, and the amino acid positions at the boundary of the excised domains, which are missing in the mutant mouse, are marked on either side of the curved line.

This image is from Kugler JE, J Biol Chem 2013 Jun 7;288(23):16690-703 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:199604

Associated
Alleles

Symbol	Name
Hmgn5^tm1.2Mbus	high-mobility group nucleosome binding domain 5; targeted mutation 1.2, Michael Bustin

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