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Caption | Purkinje cell degeneration in Agtpbp1pcd-5J/Agtpbp1pcd-5J (5J) mice. Parasagittal P25 cerebellar sections were immunostained with anti-calbindin antibody and counterstained with DAPI (nuclei show blue fluorescence). DBA/2J (WT) P25 cerebellar sections show numerous Purkinje cell neurons with extensive dendritic arborization in the molecular layer (ML). Matching sections from homozygous mutant mice (5J) display pronounced Purkinje cell loss and marked degeneration of surviving Purkinje cells. PCL = Purkinje cell layer; GCL = granule cell layer. | ||||
Copyright | This image is from Chakrabarti L, Mamm Genome 2006 Feb;17(2):103-10 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:105316 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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