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Phenotype Image Detail
Image
Caption (A) Wild-type embryo at E9.5 (B) Mttptm1Sgy/Mttptm1Sgy embryo at E9.5 with incomplete closure of the neural tube. (C) E10.5 Mttptm1Sgy/Mttptm1Sgy embryo that appears necrotic and has incomplete anterior closure of the neural tube. (D) An Mttptm1Sgy/Mttptm1Sgy embryo with exencephalus at E14.5 (E & F) Hematoxylin and eosin stained yolk sac membranes of wild-type (E) and Mttptm1Sgy/Mttptm1Sgy mouse at E10.5 showing reduced numbers of blood cells in the blood islands of the Mttptm1Sgy/Mttptm1Sgy membranes in comparison to the membranes of the wild-type mouse. Vacuolization at the basolateral surfaces of the visceral endoderm (arrow in F).
Copyright This image is from Raabe M, Proc Natl Acad Sci U S A 1998 Jul 21;95(15):8686-91. Copyright 1998 National Academy of Sciences, U.S.A. J:48934
Associated
Alleles
Symbol Name
Mttptm1Sgy microsomal triglyceride transfer protein; targeted mutation 1, Stephen G Young
Associated
Genotypes
Allelic Composition Genetic Background
Mttptm1Sgy/Mttptm1Sgy involves: 129S4/SvJae

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory