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| Caption | (A) As compared with the +/+ wild-type skeleton (lower) the skeleton of the Fgfr3tm1Wei/Fgfr3tm1Wei (upper) shows a kinky and elongated tail, as well as bent and longer long bones, especially in the femur. (B) Comparison of the femurs from the +/+ wild-type (left) and the Fgfr3tm1Wei/Fgfr3tm1Wei (right). (C-F) Histological analysis of the Fgfr3tm1Wei/Fgfr3tm1Wei reveals growth plates (D & F) are longer then the growth plates of the +/+ wild-type (C & E), which is attributable to an increase in proliferating chondrocytes. Abbreviations: hypertrophic zone (HZ); proliferating zone (PZ). | ||||
| Copyright | This image is from Wang Y, Proc Natl Acad Sci U S A 1999 Apr 13;96(8):4455-60. Copyright 1999 National Academy of Sciences, U.S.A. J:54829 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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