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| Caption | (A) The stomach of an 11 month old wild type animal opened along the greater curvature. (B) Polyps (P) of different sizes cover the entire mucosa region of the stomach of a heterozygous Smad4m4Mag littermate. (C) A section through the body of the wild type stomach shows the well organized mucosa and the muscularis region underneath. (D) A section through the body of the stomach of the heterozygous animal shows the disorganized hyperplastic mucosa region. (E) A section of the polyp (P) region in B, showing extensive proliferation of the glandular structures indicative of adenocarcinoma. The asterisk indicates a region of polyp with lymphocyte infiltration. | ||||
| Copyright | This image is from Chen Y, Mamm Genome 2006 Mar;17(3):211-9 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:106440 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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