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| Caption | H&E staining of coronal section through the palatal region of the Lhx8tm1Lmgd/Lhx8tm1Lmgd embryos at E13.5 (B), E14.5 (D) and E16.5 (F) as compared with age matched wild-type embryos (A,C, & E). Arrowheads point at the palatal shelves that were not in contact ( A,B,D & F), were in contact (C) or were completely fused (E). Arrows point at one of the upper molar tooth buds in all panels. G & H: H&E stained coronal sections through the distal region of the mandible of a wild-type (G) and Lhx8tm1Lmgd/Lhx8tm1Lmgd embryo at E16.5 with a cleft palate, showing normal development of the mandible, incisor teeth and the Meckel's cartalage in the homozygous mutant. Abbreviations: Meckel's cartilage (m) Scalebar: A-F: 200um; G-H: 80um | ||||
| Copyright | This image is from Zhao Y, Proc Natl Acad Sci U S A 1999 Dec 21;96(26):15002-6. Copyright 1999 National Academy of Sciences, U.S.A. J:59082 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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