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| Caption | A: Sagittal paraffin section of a control (either wild-type or heterozygous mice) E10.5 heart stained with hematoxylin and eosin. The myocardial wall of the common centricular chamber shows extensive trabeculation (#) and the endocardial cushions of the atrioventricular canal (*) are well developed. Also, at this stage the truncus arteriosus shows the first signs of the formation of the aorticopulmonary spiral septum. B & C: Sections of hearts from E10.5 Scn5atm1Agrc/Scn5atm1Agrc embryos. Note the well developed endocardial cushions (*) and truncus arteriosus, but little trabeculation of the ventricular wall (#). D & E: High-magnification views of the cardiomyocytes and endothelial cells from the control (D) and homozygous mouse embryos (E). Arrowheads (in B-E) indicate endothelial cell layer surrounding the trabeculated myocardium and lining the ventricular chamber. Abbreviations: truncus arteriosus (TA) Scalebar: A-C: 100um; D & E: 25um | ||||
| Copyright | This image is from Papadatos GA, Proc Natl Acad Sci U S A 2002 Apr 30;99(9):6210-5. Copyright 2002 National Academy of Sciences, U.S.A. J:76331 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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