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Phenotype Image Detail
Image
Caption A-C: Wild-type mice at 7, 10 and 20 weeks of age. D-F: Cryaatm1Wawr/Cryaatm1Wawr mice at 7, 10 and 18 weeks of age. Eyes were dialated and examined by slit lamp for lens opacity. Normal reflection of the slit lamp from the surface of the cornea and lens are visible in all panels. Light scattering within the lens, as evinced by a white haze in the photograph, is significantly higher in the homozygous mutant mice than in the wild-type mice at each age. Mild cataract is seen in the 7 week old homozygous mutant mouse lens and a dense opacity is evident in the 18 week old lens.
Copyright This image is from Brady JP, Proc Natl Acad Sci U S A 1997 Feb 4;94(3):884-9. Copyright 1997 National Academy of Sciences, U.S.A. J:38210
Associated
Alleles
Symbol Name
Cryaatm1Wawr crystallin, alpha A; targeted mutation 1, Eric F Wawrousek
Associated
Genotypes
Allelic Composition Genetic Background
Cryaatm1Wawr/Cryaatm1Wawr involves: 129/Sv * 129S4/SvJae
Cryaatm1Wawr/Cryaatm1Wawr involves: 129S4/SvJae * C57BL/6 * DBA/2

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory