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| Caption | A: Normal wild-type kidney (left) and kidney from Uoxtm1Bay/Uoxtm1Bay (right) with linear white streaks in lower cortex and medulla representative of urate deposits in renal tubules and collecting ducts. B: Microscopic view of dialated renal tubules containing bluish-pink material (urate crystals) and desquamated tubular epithelia in lumina. (Hematoxylin and eosin stain) C: Acute tubular necrosis with infiltration of neutrophils at day 14. D: Partial polarization of eosin-stained, ethanol-fixed kidney demonstrating anisotropic urate crystals in renal tubules on left and same field under full polarization on right. E: Subgross view of kidney at 5 weeks of age with moderate hydronephrosis (*) and blue foci in outer cortex (arrow). F: Higher power magnification of E demonstrating tubular atrophy and collapse on left with crowding of glomeruli compared wit hnormal renal tubules on right. Magnification: B & F: x40; C: x20; D: x110; E x5 | ||||
| Copyright | This image is from Wu X, Proc Natl Acad Sci U S A 1994 Jan 18;91(2):742-6. Copyright 1994 National Academy of Sciences, U.S.A. J:16490 | ||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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