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Phenotype Image Detail
Image
Caption Wild-type (right) Kcnq1tm1Kpfe/Kcnq1tm1Kpfe (left) comparisons of the midmodular sections of the cochlea at P0 (A), P3 (B) and P70 (C). Note the collapse of Reissner's membrane at P3 (B) and degeneration of inner and outer hair cells at P70 (C). D-F: Details of the saccule at P0 (D), P8 (E) and P70 (F).
Copyright This image is from Casimiro MC, Proc Natl Acad Sci U S A 2001 Feb 27;98(5):2526-31. Copyright 2001 National Academy of Sciences, U.S.A. J:67873
Associated
Alleles
Symbol Name
Kcnq1tm1Kpfe potassium voltage-gated channel, subfamily Q, member 1; targeted mutation 1, Karl Pfeifer
Associated
Genotypes
Allelic Composition Genetic Background
Kcnq1tm1Kpfe/Kcnq1tm1Kpfe involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/05/2024
MGI 6.24 		The Jackson Laboratory