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| Caption | Transmission electron micrographs of glomeruli and vascular pole region of wild-type (a) and Nr3c2tm1Gsc/Nr3c2tm1Gsc mice at 8 days of age. In the homozygous mice, the macula densa segment of the distal tubule (MD) was enlarged. The extraglomerular mesangium (encircled by a dotted line) showed prominent hyperplasia with granules (arrows in a and b) in almost every cell. Renin immunocytochemistry (c and e) and corresponding phase contrast pictures (d and f) of 8-day-old mice. In homozygous mutant mice (e), staining for renin at the vascular pole region is much more prominent than in wild-type mice (c). | ||||
| Copyright | This image is from Berger S, Proc Natl Acad Sci U S A 1998 Aug 4;95(16):9424-9. Copyright 1998 National Academy of Sciences, U.S.A. J:77285 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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