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Phenotype Image Detail
Image
Caption C: Five Lrp6Cd/Lrp6Gt(Ex187)Byg pups with wild-type siblings show mildly (black arrow) to severly (arrows) crooked tails. One pup has an inrregular spine (white arrowhead) whose skeletal staining (D) reveals fused vertebrae (arrow) and a hemi-vertebra (white arrowhead). A Lrp6Cd/Lrp6Gt(Ex187)Byg embryo displays exencephaly (e). Abbreviations: dorsal (d); ventral (v)
Copyright This image is from Carter M, Proc Natl Acad Sci U S A 2005 Sep 6;102(36):12843-8. Copyright 2005 National Academy of Sciences, U.S.A. J:101423
Associated
Alleles
Symbol Name
Lrp6Cd low density lipoprotein receptor-related protein 6; crooked
Lrp6Gt(Ex187)Byg low density lipoprotein receptor-related protein 6; gene trap Ex187, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Lrp6Cd/Lrp6Gt(Ex187)Byg involves: 129P2/OlaHsd * A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory