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Phenotype Image Detail
Image
Caption Histologic bone comparison of wild-type and Cyp27b1tm1Dgo/Cyp27b1tm1Dgo littermates at 4 weeks of age. A: Proximal tibial epiphysis, growth plate, and metaphysis, hematoxylin and eosin stained. B: Von Kossa stain of undermineralized sections at 4 weeks of age. Counterstaining with toluidine blue. C: Tartrate-resistant acid phosphatase (TRAP) staining of osteoclasts in the primary spongiosa. Counterstaining with methylene blue. Abbreviations: growth plate (GP); distal femur (DF); trabecular (TB); cortical bone (CB); osteiod (*) Scalebars: A (upper) 500um; (lower) 250um; B: (DF) 500um; (GP) 100um; (TB & CB) 50um C: (upper) 250um; (lower) 50um
Copyright This image is from Panda DK, Proc Natl Acad Sci U S A 2001 Jun 19;98(13):7498-503. Copyright 2001 National Academy of Sciences, U.S.A. J:70030
Associated
Alleles
Symbol Name
Cyp27b1tm1Dgo cytochrome P450, family 27, subfamily b, polypeptide 1; targeted mutation 1, David Goltzman
Associated
Genotypes
Allelic Composition Genetic Background
Cyp27b1tm1Dgo/Cyp27b1tm1Dgo involves: 129S1/Sv * 129X1/SvJ * BALB/c

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory