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Phenotype Image Detail
Image
Caption B-D: Hart's staining of the transverse sections of ligated arteries. Neointima and vascular remodleing were compared between wild-type (B), Fbln5tm1Eno/Fbln5tm1Eno carotid arteries (C) and Elntm1Dyl/Eln+ carotid arteries after 28 days of ligation. Both Fbln5tm1Eno/Fbln5tm1Eno carotid arteries and Elntm1Dyl/Eln+ carotid arteries exhibited decreased extensibility; however, there was no outward remodeling or increased neointima formation in the Elntm1Dyl/Eln+ vessel. Scalebar: 40um
Copyright This image is from Spencer JA, Proc Natl Acad Sci U S A 2005 Feb 22;102(8):2946-51. Copyright 2005 National Academy of Sciences, U.S.A. J:96831
Associated
Alleles
Symbol Name
Elntm1Dyl elastin; targeted mutation 1, Dean Y Li
Fbln5tm1Eno fibulin 5; targeted mutation 1, Eric N Olson
Associated
Genotypes
Allelic Composition Genetic Background
Fbln5tm1Eno/Fbln5tm1Eno involves: 129S6/SvEvTac * C57BL/6
Elntm1Dyl/Eln+ involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/12/2024
MGI 6.24 		The Jackson Laboratory