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| Caption | A: Ventral view of the lumbosacral skeleton of a one month old wild-type mouse showing the normal pattern of six lumbar (L1 to L6) and four sacral (S1 to S4) vertebrae. B: Hoxd11tm1Ipc/Hoxd11tm1Ipc mutant mouse displaying an additional L6-like (L7) vertebra. The next posterior vertebrae have normal sacral morphology (S1* to S4*). C: A homozygous mutant mouse with an asymmetrical transformation of S1 (S0). On the right side the transformation is very weak, whereas the left half has a morphology intermediate between L6 and S1. The next posterior vertebrae are apparently all anteriorly transformed as in the previous specimen (S1* to S4*). D: Laterodorsal view of a wild-type specimen. E: Laterodorsal view of the corresponding vertebrae of the mutant displayed in C showing the intermediate morphology of the S0 left transverse process, which has a small articular surface for the illium although it is shaped as an L6 process (curved arrow). | ||||
| Copyright | This image is from Favier B, Proc Natl Acad Sci U S A 1995 Jan 3;92(1):310-4. Copyright 1995 National Academy of Sciences, U.S.A. J:22289 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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