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| Caption | The skulls of wild type (A) and Crebbptm1Sis/Crebbp+ mouse (B) at 18.5dpc obtained by mating with BALB/c mice are shown. Note that delayed ossification of the frontal bones and large anterior frontanels are seen in the heterozygous mutant mice. The sternum and ribs of wild type (C) and a heterozygous mutant mouse (D) obtained by mating with BALB/c are indicated. Asymmetric ossification shown by * and splits are seen in the heterozygotes. Distinct holes and fissures in the xiphoid process observed in the heterozygous mutant mouse are indicated by an arrowhead. The axial bones of wild type (E) and a heterozygote (F) obtained by mating with C57BL/6 are indicated. Deficiency of the third cervical vertebra seen in the heterozygous mutant mouse indicated by an arrow. | ||||
| Copyright | This image is from Tanaka Y, Proc Natl Acad Sci U S A 1997 Sep 16;94(19):10215-20. Copyright 1997 National Academy of Sciences, U.S.A. J:42932 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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