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| Caption | Hematoxylin/eosin staining of age-matched wild-type (A, C & E) and Bbs2tm1Vcs/Bbs2tm1Vcs (B, D & F) mouse retinas. Mice were examined at 7 week ( A & B), 5 months ( C & D), and 10 months ( E & F). Some degenerative changes in the ONL are apparent in the 7 weeks old mice, although inner and outer segments are clearly distinguishable. By 5 months of age (C & D), the distinction between inner and outer segments is less apparent and the ONL is significantly thinner than in wild-type eyes. At 10 months of age (E & F), the ONL is largely degenerated and no inner or outer segments are present. Abbreviations: retinal pigment epithelium (RPE); inner segments (IS); outer segments (OS); inner nuclear layer (INL); outer nuclear layer (ONL); ganglion cell layer (GCL). Magnification: x160 | ||||
| Copyright | This image is from Nishimura DY, Proc Natl Acad Sci U S A 2004 Nov 23;101(47):16588-93. Copyright 2004 National Academy of Sciences, U.S.A. J:94467 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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