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Phenotype Image Detail
Image
Caption A: Craniofacial deformity in adult Lpar1tm1Jch/Lpar1tm1Jch mice. Note the blunted snout and more widely spaced eyes. B: Overall size decrease in homozygous mutant mice. Two 9-week-old male siblings are shown. C: Frontal cranial hemorrhage in a newborn mutant pup but not in littermates. D: Sagittal sections of an E13 mutant embryo with frontal cranial hemmorrhage (the earliest time point this phenotype was observed). Sections shown were stained to identify erythrocytes (left) using peroxidase (pseudocolored red) or Nissl substance (right) using cresyl violet.
Copyright This image is from Contos JJ, Proc Natl Acad Sci U S A 2000 Nov 21;97(24):13384-9. Copyright 2000 National Academy of Sciences, U.S.A. J:65882
Associated
Alleles
Symbol Name
Lpar1tm1Jch lysophosphatidic acid receptor 1; targeted mutation 1, Jerod Chun
Associated
Genotypes
Allelic Composition Genetic Background
Lpar1tm1Jch/Lpar1tm1Jch involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory