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Phenotype Image Detail
Image
Caption A & B: Palatal views of a wild type newborn (A) and a Gad1tm1Mrc/Gad1tm1Mrc littermate (B). The primary palate and secondary palate are indicated. C & D: Palatal view of cleared skeletal preparations of a wild type newborn (C) and homozygous mutant (D). In the mutant, the vomer and presphenoid are visible due to the cleft secondary palate. Abbreviations: primary palate (PP); secondary palate (SP); vormer (V); presphenoid (PS) Sphenoid bone (s).
Copyright This image is from Condie BG, Proc Natl Acad Sci U S A 1997 Oct 14;94(21):11451-5. Copyright 1997 National Academy of Sciences, U.S.A. J:43954
Associated
Alleles
Symbol Name
Gad1tm1Mrc glutamate decarboxylase 1; targeted mutation 1, Mario R Capecchi
Associated
Genotypes
Allelic Composition Genetic Background
Gad1tm1Mrc/Gad1tm1Mrc involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory