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Phenotype Image Detail
Image
Caption A: Radiograph of normal bone structure in a 7 month old wild type mouse. B: Radiograph of a 13 month old Col1a2oim/Col1a2oim mouse showing generalized osteopenia, marked cortical thinning, bowing of the long bones, scoliosis, sclerosis around the knee joints, and a pronounced dorsal kyphosis. C: Pelvic radiograph of the homozygous mutant mouse in B, showing bowing of the long bones, sclerosis around the knee joints, and fracture callus. Magnification: A; x1.1; B: x0.9; C: x2.0
Copyright This image is from Chipman SD, Proc Natl Acad Sci U S A 1993 Mar 1;90(5):1701-5. Copyright 1993 National Academy of Sciences, U.S.A. J:4348
Associated
Alleles
Symbol Name
Col1a2oim collagen, type I, alpha 2; osteogenesis imperfecta
Associated
Genotypes
Allelic Composition Genetic Background
Col1a2oim/Col1a2oim involves: C3H/HeJ * C57BL/6JLe

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory