About   Help   FAQ
Phenotype Image Detail
Image
Caption At 21 days of age, normal hepatic morphology consists of uniform hepatocytes with bland nuclei that contain small nucleoli (A). In Cbstm1Unc/Cbs+ mice (B), the hepatocytes have anisonucleosis and fairly prominent nucleoli and appear to be slightly larger. Cbstm1Unc/Cbstm1Unc mice (C) have enlarged pleomorphic hepatocytes with large, prominent nucleoli. The hepatocytes are frequently binucleated or multinucleated, and their cytoplasm often contains multivesicular cytoplasmic lipid droplets. Magnification: x130
Copyright This image is from Watanabe M, Proc Natl Acad Sci U S A 1995 Feb 28;92(5):1585-9. Copyright 1995 National Academy of Sciences, U.S.A. J:23321
Associated
Alleles
Symbol Name
Cbstm1Unc cystathionine beta-synthase; targeted mutation 1, University of North Carolina
Associated
Genotypes
Allelic Composition Genetic Background
Cbstm1Unc/Cbstm1Unc involves: 129P2/OlaHsd * C57BL/6J
Cbstm1Unc/Cbs+ involves: 129P2/OlaHsd * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory