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Phenotype Image Detail
Image
Caption A: Macroscopic appearance of livers from 1 week old wild type (all at left) and Ahrtm1Bra/Ahrtm1Bra (all at right) mice. B & C: Hematoxylin and eosin stained sections of livers from 1 week old wild type and homozygous mutant mice demonstrating extensive microvesicular fatty metamorphosis and extramedullary hematopoiesis in the homozygous mice. D & E: Higher power view of 1 week old wild type and mutant mouse livers. F & G: Hematoxylin and eosin stained liver sections from 2 week old wild type and homozygous mutant mice demonstrating hypercellularity and fibrosis of the portal tract in the homozygous mouse. H & I: Trichrome staining for connective tissue highlighting the portal fibrosis in the homozygous mouse versus the wild type mouse liver.
Copyright This image is from Schmidt JV, Proc Natl Acad Sci U S A 1996 Jun 25;93(13):6731-6. Copyright 1996 National Academy of Sciences, U.S.A. J:33827
Associated
Alleles
Symbol Name
Ahrtm1Bra aryl-hydrocarbon receptor; targeted mutation 1, Christopher A Bradfield
Associated
Genotypes
Allelic Composition Genetic Background
Ahrtm1Bra/Ahrtm1Bra involves: 129S1/Sv * 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory