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Caption | Morphology of E18 Cacnb1tm1Rgg/Cacnb1tm1Rgg fetuses shows a reduction in muscle mass and disorganization of the myofibrils. A & B: Transverse sections through the hindlimbs of a wild type (A) and homozygous mutant (B) fetus. Sections were cut at approximately the same position and the tibia and fibula can be seen. The amount of muscle in the homozygous mutant fetus is markedly decreased. C: Electron micrograph of a triad from a homozygous mutant fetus. D & E: Electron micrograph of muscle from wild type (D) and homozygous mutant fetus (E). Abbreviations: tibia (T); fibula (F). Scale bars: A & B: 0.3mm; D & E: 1.2um | ||||
Copyright | This image is from Gregg RG, Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13961-6. Copyright 1996 National Academy of Sciences, U.S.A. J:37052 | ||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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