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Phenotype Image Detail
Image
Caption Morphology of E18 Cacnb1tm1Rgg/Cacnb1tm1Rgg fetuses shows a reduction in muscle mass and disorganization of the myofibrils. A & B: Transverse sections through the hindlimbs of a wild type (A) and homozygous mutant (B) fetus. Sections were cut at approximately the same position and the tibia and fibula can be seen. The amount of muscle in the homozygous mutant fetus is markedly decreased. C: Electron micrograph of a triad from a homozygous mutant fetus. D & E: Electron micrograph of muscle from wild type (D) and homozygous mutant fetus (E). Abbreviations: tibia (T); fibula (F). Scale bars: A & B: 0.3mm; D & E: 1.2um
Copyright This image is from Gregg RG, Proc Natl Acad Sci U S A 1996 Nov 26;93(24):13961-6. Copyright 1996 National Academy of Sciences, U.S.A. J:37052
Associated
Alleles
Symbol Name
Cacnb1tm1Rgg calcium channel, voltage-dependent, beta 1 subunit; targeted mutation 1, Ronald G Gregg
Associated
Genotypes
Allelic Composition Genetic Background
Cacnb1tm1Rgg/Cacnb1tm1Rgg involves: 129S7/SvEvBrd

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory