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Phenotype Image Detail
Image
Caption C-E: Frem1tm1Ksek/Frem1tm1Ksek mice exhibit cryptophthalmos (C), syndactyly in the hindlimb (D), and subepidermal blistering at E14.5 (arrowheads in E). F: Electron microscopic observation of the blebs of homozygous mutant embryos demonstrate that blistering occurs between the lamina densa of the basement membrane (arrowheads) and the underlying dermis. A blister cavity is indicated by an asterisk. Abbreviation: Epi: epidermal cell
Copyright This image is from Kiyozumi D, Proc Natl Acad Sci U S A 2006 Aug 8;103(32):11981-6. Copyright 2006 National Academy of Sciences, U.S.A. J:111788
Associated
Alleles
Symbol Name
Frem1tm1Ksek Fras1 related extracellular matrix protein 1; targeted mutation 1, Kiyotoshi Sekiguchi
Associated
Genotypes
Allelic Composition Genetic Background
Frem1tm1Ksek/Frem1tm1Ksek involves: 129 * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory