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| Caption | In wild type mice (A), stria vascularis (SV) capillaries consist of a thin endothelium and pericytes, sheathed in a continuous basal lamina. Endothelial cells are sealed by extensive TJs, one of which (frame) is shown at higher magnification (B arrow). The arrowhead in B indicates the basal lamina. C-F: SV capillaries in Gjb6tm1Kwi/Gjb6tm1Kwi mice feature a wall comprising multiple cell layers (double arrows) and basal lamina sheets (arrowheads). Asterisks indicate enlarged paracellular spaces between endothelial cells, appearing as electron-transluscent zones. Scale bars: A: 2um; B: 200nm; C & D: 1um; E & F: 500nm | ||||
| Copyright | This image is from Cohen-Salmon M, Proc Natl Acad Sci U S A 2007 Apr 10;104(15):6229-6234. Copyright 2007 National Academy of Sciences, U.S.A. J:120823 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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