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| Caption | Wild type embryos (left); Jag1Mhdahtu/Jag1Mhdahtu embryos (right). A & B: Yolk sacs (still containing embryos) obtained at E11.5 show the absence of large blood vessels in the homozygous embryos. C & D: E11.5 embryos demonstrating the hemorrhaging observed in the mutant embryos. E & F: E10.5 embryos process for anti-PECAM immunohistochemistry to detect vascular defects in the embryos. Arrows indicate one of the large blood vessels in the head, which is thicker in the mutant and appears to undergo less branching in the mutant. Scale bar: 1mm in D (for A-D) and 500um in F (for E & F) | ||||
| Copyright | This image is from Kiernan AE, Proc Natl Acad Sci U S A 2001 Mar 27;98(7):3873-8. Copyright 2001 National Academy of Sciences, U.S.A. J:72108 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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