About   Help   FAQ
Phenotype Image Detail
Image
Caption Skeletal comparison between wild type and Itgb2tm2Bay/Itgb2tm2Bay mice. A: Faxitron analysis demonstrates a decreased bone density in the femurs of 5 week old Itgb2tm2Bay/Itgb2tm2Bay mice (right) as compared with their wild type counterparts (left). C: Hematoxylin and eosin staining on the metaphysis area of the femurs shows diminished trabecular bone structure in the homozygous mutant mice (right) as compared with wild type mice (left). D: Representative images of the distal femur metaphysis on microcomputed tomography analysis revealed decreased bone volume, trabecular bone number, trabecular bone thickness, and an increased trabecular bone space. E: Alizarin red and Alcian blue double skeletal staining for bone (red) and cartilage (blue) of 1 week old homozygous mutant mice (right) and wild type littermates (left)>
Copyright This image is from Miura Y, Proc Natl Acad Sci U S A 2005 Sep 27;102(39):14022-7. Copyright 2005 National Academy of Sciences, U.S.A. J:101407
Associated
Alleles
Symbol Name
Itgb2tm2Bay integrin beta 2; targeted mutation 2, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Itgb2tm2Bay/Itgb2tm2Bay B6.129S7-Itgb2tm2Bay

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory