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Phenotype Image Detail
Image
Caption White matter (hippocampal fimbria) sections of a control (A) and Arsatm1Gie/Arsatm1Gie mouse (B) stained for sulfatide with alcian blue. No staining is detected in the brain of the control mouse. White matter of the deficient mouse displays cells filled with large storage granules and linearly arranged small cellular process with small granules. C: Ultrastructure of storage material. Prismatic herringbone-like inclusions in an astrocyte of a mutant mouse. Scale bar 100um
Copyright This image is from Hess B, Proc Natl Acad Sci U S A 1996 Dec 10;93(25):14821-6. Copyright 1996 National Academy of Sciences, U.S.A. J:37978
Associated
Alleles
Symbol Name
Arsatm1Gie arylsulfatase A; targeted mutation 1, Volkmar Gieselmann
Associated
Genotypes
Allelic Composition Genetic Background
Arsatm1Gie/Arsatm1Gie involves: 129P2/OlaHsd * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory